What Is Osmosis Skincare?
Osmosis is a medical-grade skincare brand built around the idea that skin problems start beneath the surface. Most skincare products address symptoms at the outer layers. Osmosis products target the dermis - the deeper layer where collagen, elastin, and skin cell production actually happen - using a proprietary delivery system called Liposome Delivery Technology.
The brand was founded by Dr. Ben Johnson, a physician who spent years working in skin health before developing Osmosis's approach to epidermal remodeling. The line covers everything from cleansers and serums to internal wellness supplements, because Osmosis treats skin as a whole-body reflection of health.
What Makes Osmosis Different?
A few things distinguish Osmosis from standard skincare brands:
Deeper ingredient delivery. Liposome encapsulation allows active ingredients to penetrate past the stratum corneum - the surface skin barrier - and reach the living layers underneath. Most over-the-counter products stay on or near the surface.
Whole-body approach. Osmosis includes topical skincare and internal supplements in the same line. The logic: what you put in affects what shows up on the outside. Their Skin Clarifier and Regenerate supplements work alongside the topical products.
Medical-grade concentration. Osmosis products carry higher active concentrations than what you'd find at a drugstore, which is why they produce more visible results - and why patch testing new actives is always a good idea.
The Osmosis Product Line at Cleanse
Cleansers
Osmosis Skincare | Cleanse ($28-$44)
A gentle but thorough daily cleanser. Available in two sizes, suitable for morning and evening use. Works well as the foundation step for any Osmosis routine.
Serums
Osmosis serums are where the brand's technology shows most clearly. These are the high-concentration actives that do the heavy lifting.
StemFactor Serum ($150) - Osmosis's most recognized product. Contains over 600 human growth factors that signal skin cells to behave more youthfully - producing collagen, repairing damage, and thickening the dermis over time. Best for anti-aging, sun damage, and anyone who wants long-term skin improvement.
Rescue Epidermal Repair Serum ($150) - Designed for compromised, sensitized, or post-procedure skin. It accelerates the skin's repair cycle and restores barrier function. A good choice after chemical peels, laser, or for rosacea-prone skin.
Calm Serum ($94) - Formulated to reduce inflammation and redness at the source. A targeted option for reactive, sensitive, or redness-prone skin types.
Moisturizers & Masks
Hydrafirm Smoothing Cream ($78) - A firming daily moisturizer that hydrates and supports collagen structure. Works well as a day or night cream over serums.
Hydrate ($72) - A lighter hydration option for balanced to combination skin types. Clean, effective, and easy to layer.
Hydraluxe Firming Gel Mask ($60) - A treatment mask that firms and plumps. Use 1-2x per week over your serums for a visible glow boost.
Carrot Calendula Mask ($60) - A nourishing mask for dry or dull skin. Carrot seed oil and calendula deliver antioxidants and calm the skin simultaneously.
Tropical Mango Mask ($60) - Brightening and hydrating. A good option for hyperpigmentation and uneven tone.
Crepe Correct Cream ($94) - Specifically formulated for crepey skin on the neck, chest, and body. Firms and smooths thin, aging skin in areas that most face products don't address.
Lift Away ($48) - A targeted treatment that supports skin firmness and reduces sagging appearance over time.
Catalyst ($144) - An advanced skin remodeling treatment. Works at the deepest levels to improve texture, tone, and structural integrity. A strong option for anyone dealing with significant aging or scarring.
Eye & Lip Care
Illuminate Eye & Lip Treatment ($72) - Addresses dark circles, puffiness, and fine lines around the eyes and lips in one product. The growth factor technology in this formula makes it particularly effective for the delicate periorbital area.
Sun Protection
Sun Defense Elixir ($36) - A lightweight SPF elixir that provides sun protection without the heavy feel of traditional sunscreen. Works well layered under makeup or other products.
Supplements & Wellness Elixirs
Osmosis's internal products are one of the things that set the brand apart from pure topical lines.
Skin Clarifier ($68) - An internal supplement targeting acne, congestion, and inflammatory skin conditions from within. The idea: clearing the gut and lymphatic pathways reduces what shows up on the skin's surface.
Regenerate ($89) - A supplement designed to support collagen production and tissue repair internally. Pairs well with StemFactor for a full inside-out anti-aging approach.
Skin Perfection Elixir ($36) - A daily wellness elixir for overall skin health and radiance.
Mosquito Elixir ($36) - An internal supplement that works systemically to repel mosquitoes. Unique to Osmosis's holistic philosophy.
Color Cosmetics
Mineral Pressed Base ($36-$45) - A mineral foundation that doubles as skincare. Available in multiple shades, provides coverage while allowing skin to breathe. A clean option for anyone avoiding synthetic dyes and heavy formulas.
Superfood Lip Oil ($26) - A nourishing lip oil in multiple shades. Conditions while adding a glossy, healthy-looking finish. One of the most accessible entry points into the Osmosis line.
Where to Start
If you're new to Osmosis, start with the basics and build:
- Cleanser - Osmosis Cleanse
- Key serum - StemFactor for anti-aging, Rescue for sensitive/compromised skin, or Calm for redness
- Moisturizer - Hydrafirm or Hydrate depending on skin type
- SPF - Sun Defense Elixir
Add in a mask, eye treatment, or supplement once the core routine is established.
Shop Osmosis at Cleanse
Cleanse Face & Body Bar carries the full Osmosis skincare and wellness line - curated by estheticians who understand how these products fit into a complete skin health routine.
Free shipping on orders $125+.
To your wellness,
Lisa
Co-Founder, Licensed Esthetician & RN
Cleanse Face & Body Bar